Buy AHK-Cu Peptide – Premium Copper Peptide for Hair & Skin Research
AHK-Cu Peptide (Alanine-Histidine-Lysine-Cu) – Hair Growth Research Peptide
AHK-Cu (Alanine-Histidine-Lysine-Cu), also known as Copper Tripeptide-3, is a synthetic peptide complex consisting of the amino acids alanine, histidine, and lysine bound to a copper ion . It is a structural analog of the well-known GHK-Cu peptide, designed for specialized research into hair follicle growth and dermal cell proliferation . AHK-Cu is a bioactive peptide reported to promote hair growth and is widely utilized in cosmetic and dermatological research applications . This research-grade copper peptide is strictly for laboratory investigation and is not intended for human consumption.
Key Factual Details
| Attribute | Detail |
|---|---|
| Chemical Name | L-Alanyl-L-histidyl-L-lysine-Cu2+ (Copper Tripeptide-3) |
| Sequence | Ala-His-{Lys-Cu} |
| Molecular Formula | C₁₅H₂₄CuN₆O₄ |
| Molecular Weight | 415.93 g/mol |
| CAS Number | 767286-83-9 |
| Alternative CAS | 682809-81-0 (monohydrochloride form) |
| Appearance | Blue powder |
| Purity | ≥98% (HPLC verified) |
| Solubility | Water soluble |
| Classification | Copper peptide / Hair growth research peptide |
Mechanism of Action & Research Applications
Hair Growth Stimulation: AHK-Cu has demonstrated significant hair growth-promoting effects in research studies . It functions as a growth factor that increases dermal fibroblast proliferation and elevates vascular endothelial growth factor (VEGF) production while decreasing transforming growth factor-β1 (TGF-β1) secretion .
Dermal Papilla Cell Proliferation: Research shows that AHK-Cu at concentrations of 10⁻¹² to 10⁻⁹ M stimulates the elongation of human hair follicles ex vivo and promotes the proliferation of dermal papilla cells (DPCs) in vitro .
Anti-Apoptotic Effects: The peptide increases the Bcl-2/Bax ratio and reduces cleaved caspase-3 and PARP levels in treated cells, suggesting it prevents apoptosis in dermal papilla cells .
Collagen Synthesis: AHK-Cu stimulates collagen type I production in human dermal fibroblasts, with studies showing up to 300% increase over control groups .
Research Applications:
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Hair Growth Research: Investigating follicle elongation and hair cycle regulation
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Dermatological Studies: Exploring wound healing, skin regeneration, and collagen synthesis
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Anti-Aging Research: Examining extracellular matrix remodeling and skin elasticity
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Cellular Proliferation Studies: Investigating fibroblast and dermal papilla cell growth pathways
Research Parameters
All dosages are for in-vitro research use only and are not intended for human consumption.
In Vitro Research Concentrations :
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Hair follicle elongation: 10⁻¹² to 10⁻⁹ M
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DPC proliferation studies: 10⁻¹³ to 10⁻⁷ M
Topical Research Formulations :
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Concentration range: 0.1% – 0.5% (w/w) in formulations
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Vehicle: Sterile water, propylene glycol, ethanol
Storage:
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Store lyophilized powder at -20°C
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Protect from light and moisture
Order AHK-Cu Today – Request a quote for your hair growth or dermatological research project. Available in various pack sizes with Certificate of Analysis. Contact our sales team for bulk pricing and custom synthesis inquiries.











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